The objective of this paper is to employ the results from the extensive instrumentation installed on recently tested full-scale cold-formed steel (CFS)-framed buildings to reveal a deeper understanding of the behavior of the building under seismic excitations. In particular, this paper complements a companion paper that focuses on system-level design and response. Here, utilizing strategically located string potentiometers, strain gauges, and accelerometers, the responses of the walls and diaphragms are isolated from the overall building response and studied. The interaction of shear walls along a wall line, as well as across stories is studied through measured data on strains in hold-down anchors, strains on floor-to-floor strap connecting shear-wall chord studs, and displacements across shear-wall sheathing and openings. The behavior of the floor diaphragm is studied through displacements measured perpendicular to the plane of one wall of the building and accelerometers throughout the floor of the building. The results serve to highlight the subsystem-level outcomes that accompany the complex system-level response as CFS-framed buildings undergo seismic excitations.